Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | SPR | P35270 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL26662926 | 1.00 | MPO (0.70) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL2404826 | 0.99 | MPO (0.72) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL7671849 | 0.87 | HTR2A (0.60) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL29206530 | 0.86 | MPO (0.67) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL30877859 | 0.86 | MPO (0.67) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL29316397 | 0.85 | MPO (0.65) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| Iodide SCHEMBL30672198 | 0.84 | MTNR1A (0.61) | MPOMTNR1AMTNR1BSLC6A4HTR2A | |
| Iodide SCHEMBL26662781 | 0.84 | MTNR1A (0.61) | MPOMTNR1AMTNR1BSLC6A4HTR2A | |
| SCHEMBL30877838 | 0.84 | MPO (0.64) | MPONOTUMMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL29206553 | 0.84 | MPO (0.64) | MPONOTUMMTNR1AMTNR1BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12391645-B2 | N-isopropyl tryptamines and method of making monoalkylated and dialkylated tryptamine analogs | CAAMTECH, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-12391645-B2 | N-isopropyl tryptamines and method of making monoalkylated and dialkylated tryptamine analogs | CAAMTECH, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-20250197352-A1 | N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS | CAAMTECH, INC. | 2025-06-19 | — | — | US | disclosed |
| US-20250197352-A1 | N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS | CAAMTECH, INC. | 2025-06-19 | — | — | US | disclosed |
| EP-4525861-A2 | N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS | Caamtech, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225679-A2 | N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS | CAAMTECH, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391645-B2 | N-isopropyl tryptamines and method of making monoalkylated and dialkylated tryptamine analogs | INMT, SLC6A4, HNMT | MPO 1192/4885NOTUM 630/4885MTNR1A 402/4885 |
| US-20250197352-A1 | N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS | INMT, SLC6A4, HNMT | MPO 1162/4885NOTUM 634/4885MTNR1A 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.