Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29665814 | 0.84 | SMYD3 (0.58) | SMYD3TNKSDRD2DRD3CHRNA7 | |
| SCHEMBL24512945 | 0.84 | SMYD3 (0.58) | SMYD3TNKSDRD2DRD3CHRNA7 | |
| SCHEMBL29316878 | 0.80 | AHR (0.47) | MEN1KMT2ASMN1; SMN2ADRA2AMCHR1 | |
| SCHEMBL29315602 | 0.80 | SMYD3 (0.53) | SMYD3TNKSDRD2DRD3CHRNA7 | |
| SCHEMBL29316688 | 0.77 | BRD4 (0.43) | MEN1KMT2AADRA2AMCHR1 | |
| SCHEMBL29316367 | 0.77 | KDM4E (0.46) | DRD3SMN1; SMN2ADRA2AMCHR1NPC1 | |
| SCHEMBL29316658 | 0.76 | HDAC4 (0.44) | SMN1; SMN2ADRA2AMCHR1NPC1RAB9A | |
| SCHEMBL29316797 | 0.76 | MCHR1 (0.51) | MEN1KMT2AADRA2AMCHR1NPC1 | |
| SCHEMBL29316953 | 0.76 | DRD2 (0.46) | DRD2DRD3ADRA2AMCHR1NPC1 | |
| SCHEMBL21490100 | 0.74 | SMYD3 (0.74) | SMYD3TNKSCHRNA7SMN1; SMN2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239749-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS INC (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239749-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | MRGPRX2, MRGPRX1, MRGPRX4 | SMYD3 3721/4885TNKS 4689/4885DRD2 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.