Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25026640 | 0.88 | KDM4E (0.33) | HRH3PIM1L3MBTL1KDM4ERAD52 | |
| SCHEMBL24480840 | 0.83 | L3MBTL3 (0.33) | L3MBTL1L3MBTL3 | |
| SCHEMBL25814796 | 0.81 | TSHR (0.41) | — | |
| SCHEMBL24480587 | 0.81 | GBA1 (0.32) | — | |
| SCHEMBL24480318 | 0.79 | GNAO1 (0.35) | HRH3 | |
| SCHEMBL25026643 | 0.78 | GBA1 (0.32) | HRH3 | |
| SCHEMBL22518683 | 0.77 | ACHE (0.42) | L3MBTL1KDM4ERAD52L3MBTL3 | |
| SCHEMBL25856316 | 0.77 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24802104 | 0.76 | GBA1 (0.40) | HRH3L3MBTL1KDM4EL3MBTL3 | |
| SCHEMBL24480862 | 0.76 | HRH3 (0.33) | HRH3L3MBTL1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |