SCHEMBL25856316

SCHEMBL25856316

C1CC(N2CCC3(CC2)CC(CN2CCNCC2)C3)CCN1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24480971 0.80 CHRM5 (0.38) HRH3
SCHEMBL25856386 0.80 ACHE (0.38)
SCHEMBL24480848 0.77 L3MBTL3 (0.34)
SCHEMBL29317243 0.77 HRH3 (0.33) HRH3
SCHEMBL25856385 0.77
SCHEMBL25856391 0.75 MEN1 (0.33) HRH3
SCHEMBL24480318 0.75 GNAO1 (0.35) HRH3
SCHEMBL3309077 0.74 CHRM5 (0.39) HRH3
SCHEMBL13381568 0.74 CYP2D6 (0.40) HRH3
SCHEMBL24480580 0.74 GNAO1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131167-A1 COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF 海思科医药集团股份有限公司 2023-07-13 WO disclosed