Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480752 | 0.88 | NCF1 (0.39) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL22940513 | 0.84 | NCF1 (0.45) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL24480704 | 0.82 | KDM1A (0.37) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL24480754 | 0.81 | GBA1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL24480875 | 0.80 | CACNA2D1 (0.37) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL25571687 | 0.80 | NCF1 (0.41) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL24204800 | 0.79 | NCF1 (0.43) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL29317324 | 0.79 | NCF1 (0.33) | CACNA2D1CACNA1BCACNB1CACNA1CNCF1 | |
| SCHEMBL24204841 | 0.79 | ALDH1A1 (0.34) | CACNA2D1CACNA1BCACNB1CACNA1CACHE | |
| SCHEMBL25671267 | 0.78 | CHRM5 (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |