Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317410 | 0.87 | POLB (0.36) | GNAI3GNAO1GNAI1HRH3ACHE | |
| SCHEMBL22560635 | 0.86 | HRH3 (0.40) | GNAO1HRH3ACHETLR9TLR8 | |
| SCHEMBL3996073 | 0.84 | GNAI3 (0.42) | GNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL24319479 | 0.83 | CACNA2D1 (0.43) | GNAO1HRH3ACHECACNA2D1CACNA1B | |
| SCHEMBL13801431 | 0.82 | GNAI3 (0.49) | GNAI3GNAO1GNAI1ACHECACNA2D1 | |
| SCHEMBL24480645 | 0.81 | GNAO1 (0.50) | GNAI3GNAO1GNAI1HRH3ACHE | |
| SCHEMBL24233173 | 0.81 | ACHE (0.44) | HRH3ACHETLR9TLR8TLR7 | |
| SCHEMBL22520769 | 0.80 | CHRM5 (0.43) | HRH3ACHETLR9TLR8TLR7 | |
| SCHEMBL25143962 | 0.79 | ACHE (0.35) | HRH3ACHETLR9TLR8TLR7 | |
| SCHEMBL25482583 | 0.79 | ACHE (0.42) | HRH3ACHETLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |