Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480645 | 0.87 | GNAO1 (0.50) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL24481112 | 0.86 | GNAI3 (0.45) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL16188006 | 0.86 | GNAI3 (0.45) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL24480215 | 0.83 | GNAI3 (0.50) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL29317307 | 0.82 | GNAI3 (0.43) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL731212 | 0.81 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1CACNA2D1 | |
| SCHEMBL2912326 | 0.81 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1CACNA2D1 | |
| SCHEMBL14422030 | 0.81 | GBA1 (0.48) | GNAI3GNAO1GNAI1CHRM5ADRA2C | |
| SCHEMBL20873850 | 0.81 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1CACNA2D1 | |
| SCHEMBL92626 | 0.81 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | GNAI3 2377/4885GNAO1 756/4885GNAI1 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.