SCHEMBL29317376

SCHEMBL29317376

Cc1cc(C(=O)N(C)CC(=O)O)cc(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
BRD4 O60885 1/20 0.36
BRD2 P25440 1/20 0.36
BRD3 Q15059 1/20 0.36
DAO P14920 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
PIN1 Q13526 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
CTDSP1 Q9GZU7 2/20 0.34
CASP6 P55212 1/20 0.34
MCL1 Q07820 1/20 0.34
PDK1 Q15118 1/20 0.34
PDK2 Q15119 1/20 0.34
PDK3 Q15120 1/20 0.34
PDK4 Q16654 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11107022 0.78 HDAC1 (0.45) MEN1KMT2APIN1ITGB3ITGA2B
SCHEMBL23914114 0.78 KDM4E (0.47) MEN1KMT2AL3MBTL1TDP1EGLN1
SCHEMBL29317375 0.77 ACACB (0.44) KMT2AL3MBTL1TDP1CTDSP1
SCHEMBL12569434 0.76 TPMT (0.37) MEN1KMT2AL3MBTL1EGLN1PIN1
SCHEMBL13681549 0.76 SMN1; SMN2 (0.43) BRD4PDK1PDK2PDK3PDK4
SCHEMBL12302105 0.76 KMT2A (0.48) MEN1KMT2AEGLN1
SCHEMBL2282162 0.75 KMT2A (0.53) MEN1KMT2APIN1
SCHEMBL12569708 0.74 TDP1 (0.58) MEN1KMT2AL3MBTL1TDP1CTDSP1
Hydrochloric Acid SCHEMBL1372985 0.73 KMT2A (0.51) MEN1KMT2APIN1
SCHEMBL5474901 0.70 PIN1 (0.38) MEN1KMT2APIN1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT DRD3 1676/4885MEN1 4209/4885KMT2A 1962/4885
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT DRD3 1676/4885MEN1 4209/4885KMT2A 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.