SCHEMBL29317833

SCHEMBL29317833

COc1cc(Oc2ccnc3ccccc23)cc(-n2cccn2)c1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DDR2 Q16832 1/20 0.44
KAT6A Q92794 2/20 0.41
FGFR2 P21802 2/20 0.40
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
EGFR P00533 1/20 0.39
BRAF P15056 1/20 0.39
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30049820 1.00 DDR2 (0.44) DDR2KAT6AFGFR2PDGFRBPDGFRA
SCHEMBL30049315 0.89 DDR2 (0.56) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL29317844 0.89 DDR2 (0.56) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL29318171 0.87 DDR2 (0.47) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL30051021 0.87 PDGFRA (0.56) FGFR2PDGFRBPDGFRAEGFR
SCHEMBL29317863 0.87 PDGFRA (0.56) FGFR2PDGFRBPDGFRAEGFR
SCHEMBL29317851 0.86 DDR2 (0.48) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL30050332 0.86 DDR2 (0.46) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL30050689 0.86 DDR2 (0.48) DDR2FGFR2PDGFRBPDGFRAEGFR
SCHEMBL29317823 0.86 DDR2 (0.54) DDR2FGFR2PDGFRBPDGFRAEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CHENGDU ANTICANCER BIOSCIENCE LTD (CN) 2024-07-18 US disclosed
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CHENGDU ANTICANCER BIOSCIENCE LTD (CN) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CYP27A1, CPT1A, OAT DDR2 4341/4885KAT6A 782/4885FGFR2 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.