SCHEMBL29317844

SCHEMBL29317844

COc1cc(Oc2ccnc3ccc(OC)cc23)cc(-n2cccn2)c1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DDR2 Q16832 1/20 0.56
PDGFRB P09619 2/20 0.44
PDGFRA P16234 1/20 0.44
FGFR2 P21802 3/20 0.43
LMNA P02545 1/20 0.41
CSF1R P07333 1/20 0.41
KDR P35968 1/20 0.41
KDM4E B2RXH2 1/20 0.41
EGFR P00533 1/20 0.40
NCF1 P14598 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30049315 1.00 DDR2 (0.56) DDR2PDGFRBPDGFRAFGFR2LMNA
SCHEMBL29318171 0.91 DDR2 (0.47) DDR2PDGFRBPDGFRAFGFR2KDR
SCHEMBL30050689 0.90 DDR2 (0.48) DDR2PDGFRBPDGFRAFGFR2CSF1R
SCHEMBL29317856 0.90 EGFR (0.48) DDR2PDGFRBPDGFRAFGFR2EGFR
SCHEMBL29186534 0.90 DDR2 (0.46) DDR2PDGFRBPDGFRAFGFR2KDR
SCHEMBL30050332 0.90 DDR2 (0.46) DDR2PDGFRBPDGFRAFGFR2KDR
SCHEMBL29317851 0.90 DDR2 (0.48) DDR2PDGFRBPDGFRAFGFR2CSF1R
SCHEMBL29317833 0.89 DDR2 (0.44) DDR2PDGFRBPDGFRAFGFR2EGFR
SCHEMBL30049820 0.89 DDR2 (0.44) DDR2PDGFRBPDGFRAFGFR2EGFR
SCHEMBL29317863 0.88 PDGFRA (0.56) PDGFRBPDGFRAFGFR2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CHENGDU ANTICANCER BIOSCIENCE LTD (CN) 2024-07-18 US disclosed
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CHENGDU ANTICANCER BIOSCIENCE LTD (CN) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CYP27A1, CPT1A, OAT DDR2 4341/4885PDGFRB 4752/4885PDGFRA 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.