Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050689 | 1.00 | DDR2 (0.48) | DDR2PDGFRAKDRMETCSF1R | |
| SCHEMBL29317844 | 0.90 | DDR2 (0.56) | DDR2PDGFRAKDRCSF1RPDGFRB | |
| SCHEMBL30049315 | 0.90 | DDR2 (0.56) | DDR2PDGFRAKDRCSF1RPDGFRB | |
| SCHEMBL29318171 | 0.88 | DDR2 (0.47) | DDR2PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL30050332 | 0.87 | DDR2 (0.46) | DDR2PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL29317856 | 0.87 | EGFR (0.48) | DDR2PDGFRAPDGFRBFGFR2RIPK2 | |
| SCHEMBL29186534 | 0.87 | DDR2 (0.46) | DDR2PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL29317833 | 0.86 | DDR2 (0.44) | DDR2PDGFRAPDGFRBFGFR2EGFR | |
| SCHEMBL30049820 | 0.86 | DDR2 (0.44) | DDR2PDGFRAPDGFRBFGFR2EGFR | |
| SCHEMBL30050680 | 0.86 | GAK (0.46) | DDR2PDGFRAKDRFGFR2RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CHENGDU ANTICANCER BIOSCIENCE LTD (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CHENGDU ANTICANCER BIOSCIENCE LTD (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, CPT1A, OAT | DDR2 4341/4885PDGFRA 4710/4885KDR 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.