Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 2/20 | 0.56 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229927 | 0.89 | RAPGEF4 (0.55) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL361092 | 0.89 | MAOA (0.45) | ALDH1A1KDM4ETDP1POLBMAPT | |
| Lithium SCHEMBL8489531 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| Ammonia Solution, Strong SCHEMBL7552565 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| Water SCHEMBL30927594 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL602281 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL602279 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL4366607 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL8489527 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL4366615 | 0.87 | RAPGEF4 (0.53) | ALDH1A1KDM4ETDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036208-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036208-B2 | Methods for treating neurodegenerative disorders | NLN, CLN6, SNCA | ALDH1A1 3244/4885KDM4E 3838/4885TDP1 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.