Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13820047 | 0.82 | P2RX7 (0.40) | HTR1DP2RX7AHRPARP1PRKCQ | |
| SCHEMBL17442837 | 0.77 | MPO (0.51) | HTR2BMPOHTR2ACSNK2BCSNK2A1 | |
| SCHEMBL724626 | 0.74 | AHR (0.38) | HTR1DP2RX7AHRPARP1PRKCQ | |
| SCHEMBL14722562 | 0.73 | AHR (0.38) | HTR2BMPOHTR1DHTR2ACSNK2B | |
| SCHEMBL8404367 | 0.73 | AHR (0.40) | HTR1DP2RX7AHRPARP1PRKCQ | |
| SCHEMBL29364833 | 0.72 | AHR (0.50) | MPOHTR1DHTR2ACSNK2BCSNK2A1 | |
| SCHEMBL2245672 | 0.72 | AHR (0.50) | MPOHTR1DHTR2ACSNK2BCSNK2A1 | |
| SCHEMBL4729834 | 0.71 | PNMT (0.38) | CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL3869136 | 0.71 | AHR (0.48) | MPOHTR1DHTR2ACSNK2BCSNK2A1 | |
| SCHEMBL23088075 | 0.70 | CFB (0.35) | HTR2AP2RX7CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031547-B1 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-17 | — | — | EP | disclosed |