Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056780 | 1.00 | MAP4K1 (0.32) | MAP4K1SLC6A2SLC6A4CD274XIAP | |
| SCHEMBL31056754 | 0.89 | HTR4 (0.34) | SLC6A2SLC6A4XIAPBIRC2 | |
| SCHEMBL31056713 | 0.86 | SCN1A (0.32) | — | |
| SCHEMBL29324071 | 0.86 | SCN1A (0.32) | — | |
| SCHEMBL29322208 | 0.83 | PARP1 (0.38) | XIAPBIRC2 | |
| SCHEMBL31056598 | 0.76 | SLC6A2 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL29323708 | 0.76 | SLC6A2 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL29323240 | 0.76 | CA12 (0.39) | XIAPBIRC2 | |
| SCHEMBL29320165 | 0.73 | XIAP (0.34) | XIAPBIRC2 | |
| SCHEMBL31056638 | 0.72 | CD274 (0.34) | CD274XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |