Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056713 | 1.00 | SCN1A (0.32) | SCN1ASCN5ASCN9ADRD2DRD4 | |
| SCHEMBL29323710 | 0.86 | MAP4K1 (0.32) | — | |
| SCHEMBL31056780 | 0.86 | MAP4K1 (0.32) | — | |
| SCHEMBL31056754 | 0.83 | HTR4 (0.34) | — | |
| SCHEMBL29322208 | 0.78 | PARP1 (0.38) | PRMT5WDR77 | |
| SCHEMBL31056959 | 0.77 | SLC6A2 (0.34) | DRD2DRD4DRD3ADRB1ADRB2 | |
| SCHEMBL29324068 | 0.77 | SLC6A2 (0.34) | DRD2DRD4DRD3ADRB1ADRB2 | |
| SCHEMBL29323240 | 0.75 | CA12 (0.39) | ADRB1ADRB2 | |
| SCHEMBL29320165 | 0.72 | XIAP (0.34) | — | |
| SCHEMBL31056638 | 0.71 | CD274 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |