SCHEMBL29323812

SCHEMBL29323812

C=C(C)C(=O)OC(CS(=O)(=O)CCOC(=O)c1ccc(I)cc1)CS(=O)(=O)CCOC(=O)c1ccc(I)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 8/20 0.34
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 2/20 0.33
ESR1 P03372 2/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
PKM P14618 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323824 0.89 ESR1 (0.46) ALDH1A1TDP1MAPK1ESR1TSHR
SCHEMBL29323808 0.88 ADRB2 (0.38) STSALDH1A1TDP1MAPK1ESR1
SCHEMBL811460 0.77 TDP1 (0.48) ALDH1A1TDP1MAPK1ESR1TSHR
SCHEMBL29323831 0.76 TSHR (0.38) TSHR
SCHEMBL29323818 0.75 THRB (0.35) TSHR
SCHEMBL23601569 0.74 TDP1 (0.52) STSALDH1A1TDP1MAPK1ESR1
SCHEMBL22193449 0.74 TDP1 (0.56) STSALDH1A1TDP1MAPK1ESR1
SCHEMBL22193456 0.74 ALDH1A1 (0.40) ALDH1A1TDP1TSHRPOLBAPEX1
SCHEMBL22193451 0.74 TSHR (0.42) ALDH1A1MAPK1TSHRPKMHSD17B10
SCHEMBL22193454 0.72 MAPT (0.37) ALDH1A1TDP1TSHRPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed