SCHEMBL29323841

SCHEMBL29323841

C=Cc1ccc(S(=O)(=O)CC2CCOCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
CNR2 P34972 3/20 0.42
AOC2 O75106 6/20 0.42
MAOA P21397 4/20 0.42
AKT1 P31749 3/20 0.39
PIK3CA P42336 3/20 0.39
MTOR P42345 2/20 0.39
MAOB P27338 2/20 0.39
TGM2 P21980 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RORC P51449 1/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21929283 0.89 TDP1 (0.50) TDP1CNR2AOC2MAOAMAOB
SCHEMBL29323838 0.84 TDP1 (0.46) KCNH2TDP1CNR2AOC2MAOA
SCHEMBL19392557 0.80 KCNH2 (0.51) KCNH2CNR2AOC2MAOAAKT1
SCHEMBL1938684 0.79 PLCG1 (0.50) KCNH2TDP1CNR2AOC2MAOA
SCHEMBL16179163 0.79 KCNH2 (0.50) KCNH2CNR2AOC2MAOAAKT1
SCHEMBL23370164 0.79 MMP2 (0.48) KCNH2CNR2AOC2MAOAAKT1
SCHEMBL19392486 0.79 KCNH2 (0.47) KCNH2CNR2AOC2MAOAAKT1
SCHEMBL19392599 0.76 PKM (0.51) KCNH2CNR2AOC2MAOAALDH1A1
SCHEMBL19392478 0.76 KCNH2 (0.45) KCNH2CNR2AOC2MAOAAKT1
SCHEMBL20718079 0.75 ALDH1A1 (0.49) KCNH2CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed