Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | QDPR | P09417 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28961486 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL31056864 | 0.86 | NR1H2 (0.45) | NR1H2NR1H3GAANAMPTKDM4E | |
| SCHEMBL29326644 | 0.85 | NR1H2 (0.44) | NR1H2NR1H3GAANAMPTRXRA | |
| SCHEMBL29328205 | 0.84 | NR1H2 (0.44) | NR1H2NR1H3GAANAMPTKDM4E | |
| SCHEMBL29326263 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL29324155 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL4967606 | 0.78 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL5529036 | 0.78 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL4967238 | 0.78 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL30736753 | 0.77 | NAMPT (0.52) | NAMPTQDPREEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |