SCHEMBL2932417

SCHEMBL2932417

O=C(O)CC(C(=O)O)c1c[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
PKM P14618 1/20 0.76
CTSK P43235 1/20 0.59
MGAM O43451 10/20 0.56
GAA P10253 10/20 0.56
SI P14410 10/20 0.56
MGAM2 Q2M2H8 10/20 0.56
GPR84 Q9NQS5 2/20 0.53
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
FFAR1 O14842 1/20 0.50
APAF1 O14727 1/20 0.49
POLB P06746 1/20 0.49
RECQL P46063 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.49
MPO P05164 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834853 1.00 MAPT (0.76) MAPTMEN1KMT2APKMCTSK
SCHEMBL6835648 1.00 MAPT (0.76) MAPTMEN1KMT2APKMCTSK
SCHEMBL15747704 0.87 MEN1 (1.00) MAPTMEN1KMT2APKMCTSK
SCHEMBL11269915 0.84 MEN1 (0.68) MAPTMEN1KMT2APKMCTSK
SCHEMBL148211 0.84 MAPT (0.68) MAPTMEN1KMT2APKMCTSK
SCHEMBL2087167 0.83 MAPT (0.66) MAPTMEN1KMT2APKMCTSK
SCHEMBL6288559 0.83 MGAM (0.57) MAPTMEN1KMT2APKMMGAM
SCHEMBL24493803 0.82 MAPT (0.72) MAPTMEN1KMT2APKMCTSK
SCHEMBL24493801 0.82 MAPT (0.72) MAPTMEN1KMT2APKMCTSK
SCHEMBL20553142 0.82 GPR84 (0.68) MAPTMEN1KMT2APKMCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753297-B2 TREATING A PLANT WITH AN INDOLE-3-CARBOXYLIC ACID COMPOUND FOR PROMOTING GROWTH IN PLANTS HAMMER CHARLES (US) 2004-06-22 US claimed
US-20030158043-A1 Use of indole-3-succinic acid as auxin HAMMER CHARLES (US) 2003-08-21 US claimed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
EP-0733112-B1 CYTOCHROME P-450 MONOOXYGENASES ROYAL VETERINARY & AGRICULTURA (DK) 2007-01-10 EP disclosed
EP-0703983-B9 REGULATION OF PLANT GROWTH ROTHAMSTED RES LTD (GB) 2005-07-20 EP disclosed
EP-0589841-B1 Methods for the production of hybrid seed SYNGENTA PARTICIPATIONS AG (CH) 2005-05-04 EP disclosed
EP-0703983-B1 REGULATION OF PLANT GROWTH ROTHAMSTED RES LTD (GB) 2005-03-23 EP disclosed
US-6753297-B2 TREATING A PLANT WITH AN INDOLE-3-CARBOXYLIC ACID COMPOUND FOR PROMOTING GROWTH IN PLANTS HAMMER CHARLES (US) 2004-06-22 US disclosed
US-6753297-B2 TREATING A PLANT WITH AN INDOLE-3-CARBOXYLIC ACID COMPOUND FOR PROMOTING GROWTH IN PLANTS HAMMER CHARLES (US) 2004-06-22 US disclosed
US-6753297-B2 TREATING A PLANT WITH AN INDOLE-3-CARBOXYLIC ACID COMPOUND FOR PROMOTING GROWTH IN PLANTS HAMMER CHARLES (US) 2004-06-22 US disclosed
EP-0578611-B1 Anther-specific cDNA sequences, genomic DNA sequences and recombinant DNA sequences SYNGENTA PARTICIPATIONS AG (CH) 2003-11-26 EP disclosed
EP-0703987-A1 CHIMERIC PLANT GENES POSSESSING INDEPENDENT REGULATORY SEQUENCES Novartis AG (CH) 1996-04-03 EP disclosed
WO-1995016041-A1 CYTOCHROME P-450 MONOOXYGENASES CIBA-GEIGY AG (CH) 1995-06-15 WO disclosed
WO-1995000652-A1 CHIMERIC PLANT GENES POSSESSING INDEPENDENT REGULATORY SEQUENCES CIBA-GEIGY AG (CH) 1995-01-05 WO disclosed
EP-0589841-A2 Methods for the production of hybrid seed CIBA-GEIGY AG (CH) 1994-03-30 EP disclosed
EP-0578611-A1 Anther-specific cDNA sequences, genomic DNA sequences and recombinant DNA sequences CIBA-GEIGY AG (CH) 1994-01-12 EP disclosed
EP-0519869-A2 A receptor protein kinase gene encoded at the self-incompatibility locus CIBA-GEIGY AG (CH) 1992-12-23 EP disclosed
EP-0478502-A2 Histidinol dehydrogenase protein, DNA and muteins and transgenic plants thereof CIBA-GEIGY AG (CH) 1992-04-01 EP disclosed
EP-0436467-A2 Expression of S-locus specific glycoprotein gene in transgenic plants CIBA-GEIGY AG (CH) 1991-07-10 EP disclosed
EP-0396124-A2 Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders G.D. Searle & Co. (US) 1990-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158043-A1 Use of indole-3-succinic acid as auxin SPIN3, SUCNR1, SUMO3 MAPT 2604/4885MEN1 4053/4885KMT2A 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.