SCHEMBL6834853

SCHEMBL6834853

O=C(O)C[C@@H](C(=O)O)c1c[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
PKM P14618 1/20 0.76
CTSK P43235 1/20 0.59
MGAM O43451 10/20 0.56
GAA P10253 10/20 0.56
SI P14410 10/20 0.56
MGAM2 Q2M2H8 10/20 0.56
GPR84 Q9NQS5 2/20 0.53
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
FFAR1 O14842 1/20 0.50
APAF1 O14727 1/20 0.49
POLB P06746 1/20 0.49
RECQL P46063 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.49
MPO P05164 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932417 1.00 MAPT (0.76) MAPTMEN1KMT2APKMCTSK
SCHEMBL6835648 1.00 MAPT (0.76) MAPTMEN1KMT2APKMCTSK
SCHEMBL15747704 0.87 MEN1 (1.00) MAPTMEN1KMT2APKMCTSK
SCHEMBL11269915 0.84 MEN1 (0.68) MAPTMEN1KMT2APKMCTSK
SCHEMBL148211 0.84 MAPT (0.68) MAPTMEN1KMT2APKMCTSK
SCHEMBL2087167 0.83 MAPT (0.66) MAPTMEN1KMT2APKMCTSK
SCHEMBL6288559 0.83 MGAM (0.57) MAPTMEN1KMT2APKMMGAM
SCHEMBL24493803 0.82 MAPT (0.72) MAPTMEN1KMT2APKMCTSK
SCHEMBL24493801 0.82 MAPT (0.72) MAPTMEN1KMT2APKMCTSK
SCHEMBL20553142 0.82 GPR84 (0.68) MAPTMEN1KMT2APKMCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753297-B2 TREATING A PLANT WITH AN INDOLE-3-CARBOXYLIC ACID COMPOUND FOR PROMOTING GROWTH IN PLANTS HAMMER CHARLES (US) 2004-06-22 US disclosed
US-20030158043-A1 Use of indole-3-succinic acid as auxin HAMMER CHARLES (US) 2003-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158043-A1 Use of indole-3-succinic acid as auxin SPIN3, SUCNR1, SUMO3 MAPT 2604/4885MEN1 4053/4885KMT2A 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.