SCHEMBL29324252

SCHEMBL29324252

CC(C)(C)OC(=O)N1CCC(C(F)(F)C(=O)Nc2cccc3c(C4CCC(=O)NC4=O)noc23)CC1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 15/20 0.47
CRBN Q96SW2 15/20 0.47
HDAC4 P56524 2/20 0.36
GPR119 Q8TDV5 1/20 0.36
HDAC6 Q9UBN7 1/20 0.34
GRAMD1A Q96CP6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324152 0.86 DDB1 (0.49) DDB1CRBNGPR119
SCHEMBL29321735 0.84 DDB1 (0.48) DDB1CRBN
SCHEMBL29324256 0.84 CRBN (0.37) DDB1CRBN
SCHEMBL29324610 0.82 DDB1 (0.44) DDB1CRBN
SCHEMBL31323505 0.82 DDB1 (0.54) DDB1CRBNGPR119
SCHEMBL29324248 0.79 SMN1; SMN2 (0.41) HDAC4GPR119
SCHEMBL31323670 0.79 DDB1 (0.50) DDB1CRBN
SCHEMBL31323705 0.78 DDB1 (0.47) DDB1CRBNGPR119
SCHEMBL31443980 0.78 DDB1 (0.52) DDB1CRBNGPR119
SCHEMBL31443625 0.77 DDB1 (0.51) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed