SCHEMBL29324256

SCHEMBL29324256

O=C1CCC(c2noc3c(NC(=O)C(F)(F)C4CCNCC4)cccc23)C(=O)N1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 18/20 0.37
DDB1 Q16531 16/20 0.37
SSTR4 P31391 1/20 0.34
ADRA2A P08913 1/20 0.32
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324252 0.84 DDB1 (0.47) CRBNDDB1
SCHEMBL29321737 0.79 ALDH1A1 (0.38) CRBNDDB1
SCHEMBL29324610 0.78 DDB1 (0.44) CRBNDDB1
SCHEMBL31323635 0.75 DDB1 (0.45) CRBNDDB1SSTR4
SCHEMBL23117078 0.73 CRBN (0.49) CRBNDDB1
SCHEMBL31443853 0.73 CRBN (0.49) CRBNDDB1
SCHEMBL29323930 0.73 CYP2C19 (0.48) CRBNDDB1
SCHEMBL29324618 0.72 DDB1 (0.37) CRBNDDB1
SCHEMBL31323586 0.71 DDB1 (0.49) CRBNDDB1
SCHEMBL29324611 0.71 CRBN (0.58) CRBNDDB1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed