SCHEMBL29324152

SCHEMBL29324152

CC(C)(C)OC(=O)N1CCC(C(F)(F)C(=O)Nc2cccc3c(C4CCC(=O)NC4=O)coc23)CC1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 13/20 0.49
CRBN Q96SW2 13/20 0.49
CCR8 P51685 1/20 0.36
GPR119 Q8TDV5 1/20 0.35
TGFBR1 P36897 1/20 0.35
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324252 0.86 DDB1 (0.47) DDB1CRBNGPR119
SCHEMBL29323213 0.84 DDB1 (0.49) DDB1CRBNKDM4E
SCHEMBL29324151 0.77 L3MBTL1 (0.41) CCR8GPR119TGFBR1KDM4EPKM
SCHEMBL29324244 0.76 TGFBR1 (0.41) CCR8GPR119TGFBR1PTPN2PTPN1
SCHEMBL29322908 0.76 DDB1 (0.47) DDB1CRBNGPR119
SCHEMBL29324248 0.72 SMN1; SMN2 (0.41) CCR8GPR119TGFBR1PTPN2PTPN1
SCHEMBL29324998 0.71 CYP2C19 (0.50) DDB1CRBNKDM4E
SCHEMBL24950364 0.71 DDB1 (0.54) DDB1CRBNGPR119
SCHEMBL29197470 0.70 DDB1 (0.56) DDB1CRBNGPR119KDM4E
SCHEMBL29197120 0.70 DDB1 (0.56) DDB1CRBNGPR119KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed