SCHEMBL29324618

SCHEMBL29324618

O=CC1CCN(CC(=O)Nc2cccc3c(C4CCC(=O)NC4=O)noc23)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 5/20 0.37
CRBN Q96SW2 5/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MAP1LC3B Q9GZQ8 2/20 0.36
CCNE2 O96020 3/20 0.35
CCNE1 P24864 3/20 0.35
CDK2 P24941 3/20 0.35
CYP2C19 P33261 2/20 0.35
PARP1 P09874 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
POLB P06746 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29321737 0.89 ALDH1A1 (0.38) DDB1CRBNALDH1A1KDM4EMAP1LC3B
SCHEMBL29323930 0.88 CYP2C19 (0.48) DDB1CRBNALDH1A1KDM4ECCNE2
SCHEMBL29324615 0.85 ALDH1A1 (0.37) DDB1CRBNALDH1A1KDM4ECCNE2
SCHEMBL29321735 0.83 DDB1 (0.48) DDB1CRBNPARP1
SCHEMBL29323900 0.75 CYP2C19 (0.47) DDB1CRBNALDH1A1KDM4ECCNE2
SCHEMBL29324610 0.74 DDB1 (0.44) DDB1CRBN
SCHEMBL29324998 0.72 CYP2C19 (0.50) DDB1CRBNALDH1A1KDM4EMAP1LC3B
SCHEMBL30662928 0.72 DDB1 (0.58) DDB1CRBNALDH1A1KDM4ECYP2C19
SCHEMBL24141422 0.72 DDB1 (0.57) DDB1CRBNALDH1A1KDM4ECYP2C19
SCHEMBL29324256 0.72 CRBN (0.37) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed