Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324351 | 0.89 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL13008033 | 0.83 | LMNA (0.50) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL10612962 | 0.81 | HPGD (0.74) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL29324305 | 0.81 | CNR1 (0.48) | KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL29324375 | 0.80 | PDE4A (0.47) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL4656142 | 0.76 | LMNA (0.53) | TDP1KMT2ALMNAMAPTPOLB | |
| SCHEMBL5255090 | 0.76 | LMNA (0.46) | KDM4EALDH1A1HPGDHSD17B10PDE4A | |
| SCHEMBL11081172 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL4653711 | 0.75 | P2RX3 (0.41) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL5425662 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |