SCHEMBL29324615

SCHEMBL29324615

COC(OC)C1CCN(CC(=O)Nc2cccc3c(C4CCC(=O)NC4=O)noc23)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
MAPT P10636 4/20 0.36
DDB1 Q16531 3/20 0.36
CRBN Q96SW2 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CCNE2 O96020 4/20 0.36
CCNE1 P24864 4/20 0.36
CDK2 P24941 4/20 0.36
KDM4E B2RXH2 1/20 0.35
CDK4 P11802 3/20 0.35
CCND1 P24385 3/20 0.35
CYP2C19 P33261 1/20 0.35
ALPL P05186 1/20 0.34
GAA P10253 1/20 0.34
ALPG P10696 1/20 0.34
PIK3CA P42336 1/20 0.34
PRKDC P78527 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323930 0.87 CYP2C19 (0.48) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL29321737 0.86 ALDH1A1 (0.38) ALDH1A1DDB1CRBNCCNE2CCNE1
SCHEMBL29324618 0.85 DDB1 (0.37) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL29321735 0.83 DDB1 (0.48) DDB1CRBN
SCHEMBL29324610 0.76 DDB1 (0.44) DDB1CRBN
SCHEMBL29323900 0.74 CYP2C19 (0.47) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL30662928 0.72 DDB1 (0.58) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL29324998 0.72 CYP2C19 (0.50) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL24141401 0.72 DDB1 (0.55) ALDH1A1DDB1CRBNCCNE2CCNE1
SCHEMBL24141422 0.71 DDB1 (0.57) ALDH1A1MAPTDDB1CRBNMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed