Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324204 | 0.85 | PDK1 (0.36) | SSTR4 | |
| SCHEMBL18538051 | 0.71 | SSTR4 (0.35) | SSTR4 | |
| SCHEMBL18538047 | 0.70 | ADORA2A (0.38) | SSTR4ADORA2AADORA2B | |
| SCHEMBL18538062 | 0.70 | ADORA2A (0.39) | SSTR4ADORA2AADORA2B | |
| SCHEMBL18538064 | 0.69 | ADORA2A (0.41) | SSTR4ADORA2AADORA2B | |
| SCHEMBL30480710 | 0.66 | ADORA2A (0.45) | ADORA2AADORA2B | |
| SCHEMBL613838 | 0.66 | ADORA2A (0.45) | ADORA2AADORA2B | |
| SCHEMBL18538042 | 0.66 | MAPK8 (0.33) | SSTR4 | |
| SCHEMBL18538053 | 0.66 | MAPK8 (0.36) | SSTR4ADORA2AADORA2B | |
| SCHEMBL18538063 | 0.66 | MEN1 (0.37) | SSTR4ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | SSTR4 1328/4885ADORA2A 1308/4885ADORA2B 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.