Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908047 | 1.00 | GPR119 (0.34) | GPR119HSD11B1NR1H2NR1H3KDM1A | |
| SCHEMBL24363777 | 0.86 | RORC (0.34) | GPR119HSD11B1NR1H2NR1H3 | |
| SCHEMBL29081865 | 0.86 | RORC (0.34) | GPR119HSD11B1NR1H2NR1H3 | |
| SCHEMBL24363854 | 0.86 | RORC (0.34) | GPR119HSD11B1NR1H2NR1H3 | |
| SCHEMBL25915727 | 0.77 | NR1H2 (0.38) | GPR119HSD11B1NR1H2KDM1A | |
| SCHEMBL29346540 | 0.77 | NR1H2 (0.38) | GPR119HSD11B1NR1H2KDM1A | |
| SCHEMBL30551599 | 0.76 | MMP13 (0.35) | GPR119NR1H2NR1H3 | |
| SCHEMBL29324565 | 0.76 | GPR119 (0.35) | GPR119KDM1A | |
| SCHEMBL29081837 | 0.75 | HSD11B1 (0.33) | GPR119HSD11B1NR1H2NR1H3KDM1A | |
| SCHEMBL30551600 | 0.75 | NR1H2 (0.32) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | GPR119 216/4885HSD11B1 807/4885NR1H2 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.