Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23872165 | 0.84 | ALOX5AP (0.36) | ALOX5APFGFR2 | |
| SCHEMBL23478913 | 0.76 | PDGFRB (0.48) | ALOX5APPDGFRBPDGFRA | |
| SCHEMBL21900465 | 0.74 | CYP1A2 (0.41) | PSMB5 | |
| SCHEMBL12169540 | 0.70 | ALOX5AP (0.40) | ALOX5AP | |
| SCHEMBL12416706 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL24838681 | 0.68 | TET2 (0.40) | ALOX5AP | |
| SCHEMBL25800415 | 0.68 | TET2 (0.37) | ALOX5AP | |
| SCHEMBL12169273 | 0.67 | ALOX5AP (0.41) | ALOX5AP | |
| SCHEMBL9967854 | 0.67 | POLB (0.38) | ALOX5AP | |
| SCHEMBL22326646 | 0.67 | CYP1A2 (0.38) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | PSMB5 2594/4885ALOX5AP 317/4885PDGFRB 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.