SCHEMBL29324843

SCHEMBL29324843

CC(=O)c1cccc(CC(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 6/20 0.51
PARP1 P09874 2/20 0.48
EPHX1 P07099 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
PKM P14618 1/20 0.43
POLB P06746 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324842 0.88 GPR119 (0.49) GPR119PARP1EPHX1MEN1KMT2A
SCHEMBL7243170 0.78 GPR119 (0.47) GPR119PARP1EPHX1MEN1KMT2A
SCHEMBL7243177 0.78 DRD2 (0.47) GPR119EPHX1MEN1KMT2AALDH1A1
SCHEMBL25003975 0.77 GPR119 (0.48) GPR119MEN1KMT2AMAPTKDM4E
SCHEMBL29324845 0.76 MAPK8 (0.45) GPR119EPHX1MEN1KMT2AALDH1A1
SCHEMBL27618214 0.73 KDM4E (0.54) GPR119MAPTKDM4ELMNAPKM
SCHEMBL3642671 0.73 MEN1 (0.57) GPR119EPHX1MEN1KMT2AALDH1A1
SCHEMBL654137 0.73 LMNA (0.60) GPR119EPHX1MEN1KMT2AALDH1A1
SCHEMBL2636671 0.73 MEN1 (0.57) GPR119EPHX1MEN1KMT2AALDH1A1
SCHEMBL5868022 0.73 GPR119 (0.56) GPR119EPHX1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed