SCHEMBL29324845

SCHEMBL29324845

CC(C)(C)OC(=O)N1CCC(NC(=O)Cc2cccc3c(O)cc(=O)oc23)CC1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 2/20 0.45
GPR119 Q8TDV5 5/20 0.44
KDM4E B2RXH2 2/20 0.44
EPHX1 P07099 1/20 0.42
BRD4 O60885 1/20 0.42
EPHX2 P34913 1/20 0.41
PKM P14618 1/20 0.41
ANO1 Q5XXA6 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM1A O60341 1/20 0.41
ALDH1A1 P00352 1/20 0.40
ACHE P22303 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324505 0.78 CHRM2 (0.43) EPHX2CA12CA1CA2KDM1A
SCHEMBL7243177 0.76 DRD2 (0.47) GPR119KDM4EEPHX1MEN1KMT2A
SCHEMBL7243170 0.76 GPR119 (0.47) MAPK8GPR119KDM4EEPHX1PKM
SCHEMBL29324843 0.76 GPR119 (0.51) GPR119KDM4EEPHX1PKMCA12
SCHEMBL29324244 0.76 TGFBR1 (0.41) GPR119KDM4EPKMRAB9A
SCHEMBL29324050 0.75 CHRM2 (0.47) MAPK8KDM4ECA12CA1CA2
SCHEMBL29324722 0.75 GPR119 (0.39) GPR119KDM4EPKMKDM1A
SCHEMBL29324846 0.75 KDM4E (0.49) GPR119KDM4EMEN1KMT2AALDH1A1
SCHEMBL29324842 0.72 GPR119 (0.49) GPR119KDM4EEPHX1EPHX2MEN1
SCHEMBL29324503 0.72 CHRM2 (0.42) KDM4ECA12CA1CA2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed