SCHEMBL293257

SCHEMBL293257

Cc1ccc(N(c2ccc(CO)cc2)c2ccc(CO)cc2)cc1C

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 10/20 0.54
S100B P04271 1/20 0.35
ALDH1A1 P00352 4/20 0.35
LMNA P02545 3/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
SIRT5 Q9NXA8 1/20 0.35
MAPT P10636 2/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009467 1.00 S1PR1 (0.54) S1PR1S100BALDH1A1LMNARAB9A
SCHEMBL12190212 0.95 S1PR1 (0.50) S1PR1S100BALDH1A1LMNARAB9A
SCHEMBL279460 0.95 S1PR1 (0.50) S1PR1
SCHEMBL12960555 0.93 S1PR1 (0.52) S1PR1ALDH1A1LMNAMEN1KMT2A
SCHEMBL14371522 0.85 S1PR1 (0.44) S1PR1S100BALDH1A1LMNARAB9A
SCHEMBL19018168 0.85 S1PR1 (0.44) S1PR1S100BALDH1A1LMNARAB9A
SCHEMBL8078470 0.84 S1PR1 (0.45) S1PR1
SCHEMBL21727707 0.84 S1PR1 (0.41) S1PR1S100BALDH1A1RAB9ANPC1
SCHEMBL10062458 0.84 S1PR1 (0.41) S1PR1S100BALDH1A1RAB9ANPC1
SCHEMBL10066014 0.83 ALDH1A1 (0.42) S1PR1S100BALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735032-B2 Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-05-27 US disclosed
US-8309285-B2 Protective overcoat layer and photoreceptor including same XEROX CORPORATION (US) 2012-11-13 US disclosed
US-8309285-B2 Protective overcoat layer and photoreceptor including same XEROX CORPORATION (US) 2012-11-13 US disclosed
US-8309285-B2 Protective overcoat layer and photoreceptor including same XEROX CORPORATION (US) 2012-11-13 US disclosed
EP-1808732-B1 Photoreceptor with Overcoat Layer XEROX CORP (US) 2012-03-14 EP disclosed
US-8097388-B2 Crosslinking outer layer and process for preparing the same XEROX CORPORATION (US) 2012-01-17 US disclosed
US-8097388-B2 Crosslinking outer layer and process for preparing the same XEROX CORPORATION (US) 2012-01-17 US disclosed
US-8097388-B2 Crosslinking outer layer and process for preparing the same XEROX CORPORATION (US) 2012-01-17 US disclosed
US-8029957-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2011-10-04 US disclosed
US-8029957-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2011-10-04 US disclosed
US-20070087276-A1 Phenolic hole transport polymers XEROX CORPORATON. 2007-04-19 US disclosed
EP-1775637-A1 Phenolic hole transport polymers Xerox Corporation (US) 2007-04-18 EP disclosed
EP-1775637-A1 Phenolic hole transport polymers Xerox Corporation (US) 2007-04-18 EP disclosed
EP-1775638-A1 Photoconductive members, crosslinked phenol resin, an overcoat coating composition, a process for production Xerox Corporation (US) 2007-04-18 EP disclosed
US-7205080-B2 Arylamine compound, charge transport material, electrophotographic photoreceptor, image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2007-04-17 US disclosed
US-7205080-B2 Arylamine compound, charge transport material, electrophotographic photoreceptor, image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2007-04-17 US disclosed
US-20070048636-A1 Photoconductive imaging members XEROX CORPORATION (US) 2007-03-01 US disclosed
US-20070048636-A1 Photoconductive imaging members XEROX CORPORATION (US) 2007-03-01 US disclosed
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION 2007-01-25 US disclosed
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member ARNT, STUB1, FLOT1 S1PR1 274/4885S100B 2814/4885ALDH1A1 1207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.