SCHEMBL293258

SCHEMBL293258

CNc1cc(N)ccc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
CASP1 P29466 3/20 0.52
CYP3A4 P08684 2/20 0.48
TSHR P16473 2/20 0.48
PDE10A Q9Y233 1/20 0.43
MAPT P10636 5/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RECQL P46063 1/20 0.41
PLA2G7 Q13093 1/20 0.38
SIGMAR1 Q99720 3/20 0.38
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633200 1.00 ALDH1A1 (0.54) ALDH1A1CASP1CYP3A4TSHRPDE10A
Hydrochloric Acid SCHEMBL11453440 0.98 ALDH1A1 (0.52) ALDH1A1CASP1CYP3A4TSHRPDE10A
Hydrochloric Acid SCHEMBL11438180 0.98 ALDH1A1 (0.52) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL10735215 0.85 ALDH1A1 (0.45) ALDH1A1CASP1CYP3A4TSHRMAPT
SCHEMBL31621883 0.81 ALDH1A1 (0.54) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL3110533 0.81 ALDH1A1 (0.54) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL8033091 0.80 PRKCI (0.41) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL12065127 0.79 ALDH1A1 (0.52) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL22778507 0.79 ALDH1A1 (0.52) ALDH1A1CASP1CYP3A4TSHRPDE10A
SCHEMBL14541440 0.79 PLA2G7 (0.50) ALDH1A1CASP1CYP3A4TSHRPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 US claimed
EP-1819341-A2 IL-12 MODULATORY COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-08-22 EP claimed
US-20060223996-A1 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2006-10-05 US claimed
WO-2006053227-A2 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORP. (US) 2006-05-18 WO claimed
US-12410276-B2 Method of recycling polyurethane materials CARPENTER ENGINEERED FOAMS BELGIUM BV (BE) 2025-09-09 US disclosed
EP-4010414-B1 IMPROVED METHOD OF RECYCLING POLYURETHANE MATERIALS CARPENTER ENG FOAMS BELGIUM BV (BE) 2025-06-18 EP disclosed
CN-115003660-B Adhesive composition, laminate and package DIC株式会社 2024-08-23 CN disclosed
WO-2024133871-A1 PIR CHEMICAL RECYCLING BY ALKALINE CLEAVAGE RECTICEL (BE) 2024-06-27 WO disclosed
WO-2024128009-A1 ADHESIVE COMPOSITION, MULTILAYER BODY AND PACKAGING MATERIAL DIC株式会社 2024-06-20 WO disclosed
US-11926767-B2 Adhesive composition, laminate, and package DIC CORPORATION (JP) 2024-03-12 US disclosed
EP-4328229-A2 SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2024-02-28 EP disclosed
EP-3129353-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2024-02-28 EP disclosed
US-4196145-A OXIDATION COLOR DYES CLAIROL INCORPORATED (US) 1980-04-01 US disclosed
EP-0007484-A1 Process for the preparation of a polyurethane from an organic polyisocyanate or polyisothiocyanate and three different active hydrogen atom containing compounds THE DOW CHEMICAL COMPANY (US) 1980-02-06 EP disclosed
US-4147711-A Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom RHONE-POULENC INDUSTRIES (FR) 1979-04-03 US disclosed
US-4092102-A HAIR DYES, OXIDATION DYES CLAIROL INCORPORATED (US) 1978-05-30 US disclosed
US-4088670-A P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID RHONE-POULENC INDUSTRIES (FR) 1978-05-09 US disclosed
US-4057518-A Process for the manufacture of heat resistant multicellular materials RHONE-POULENC INDUSTRIES (FR) 1977-11-08 US disclosed
US-4013600-A STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1977-03-22 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223996-A1 IL-12 modulatory compounds IL2, IL4, IFNG ALDH1A1 1381/4885CASP1 231/4885CYP3A4 717/4885
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS IL2, IL4, IFNG ALDH1A1 1381/4885CASP1 231/4885CYP3A4 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.