Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326054 | 0.85 | IL1B (0.39) | ALDH1A1PDE8BTSHRLMNAMEN1 | |
| SCHEMBL1598122 | 0.80 | HCRTR1 (0.49) | ALDH1A1OPRD1APPHTR1AADRA2A | |
| SCHEMBL1598119 | 0.80 | HCRTR1 (0.49) | ALDH1A1OPRD1APPHTR1AADRA2A | |
| SCHEMBL29326138 | 0.77 | TRPV1 (0.44) | OPRD1PRMT5TRPV1 | |
| SCHEMBL29131873 | 0.77 | OPRD1 (0.46) | ALDH1A1OPRD1PRMT5TSHRLMNA | |
| SCHEMBL29131871 | 0.77 | OPRD1 (0.46) | ALDH1A1OPRD1PRMT5TSHRLMNA | |
| SCHEMBL4237375 | 0.77 | PDE8B (0.43) | ALDH1A1PDE8BOPRD1PRMT5TSHR | |
| SCHEMBL15056219 | 0.76 | PRMT5 (0.43) | ALDH1A1OPRD1PRMT5TSHRLMNA | |
| SCHEMBL15056838 | 0.76 | PRMT5 (0.43) | ALDH1A1OPRD1PRMT5TSHRLMNA | |
| SCHEMBL15056300 | 0.76 | PRMT5 (0.43) | ALDH1A1OPRD1PRMT5TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | ALDH1A1 1683/4885PDE8B 3592/4885OPRD1 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.