Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377727 | 0.93 | CYP11B1 (0.48) | CYP11B1CYP11B2PRMT5WDR77CYP2D6 | |
| SCHEMBL27377600 | 0.91 | NPEPPS (0.43) | CYP11B1CYP11B2PRMT5WDR77CYP2D6 | |
| SCHEMBL29326224 | 0.89 | NPEPPS (0.48) | CYP2C9CYP2C19NPEPPSTDP1CYP1A2 | |
| SCHEMBL29328549 | 0.83 | FEN1 (0.53) | CYP11B1CYP11B2NPEPPSKDM4EHTT | |
| SCHEMBL27377718 | 0.83 | NPEPPS (0.41) | CYP11B1CYP11B2PRMT5WDR77CYP2C9 | |
| SCHEMBL27191731 | 0.83 | TNKS2 (0.46) | CYP11B1CYP11B2CYP2C9CYP2C19NPEPPS | |
| SCHEMBL29326223 | 0.83 | FEN1 (0.58) | CYP2C9CYP2C19NPEPPSTDP1CYP1A2 | |
| SCHEMBL29326265 | 0.83 | PTGES (0.46) | CYP11B1CYP11B2CYP2C9CYP2C19NPEPPS | |
| SCHEMBL27377884 | 0.83 | KDM4E (0.43) | CYP11B1CYP11B2CYP2C9CYP2C19NPEPPS | |
| SCHEMBL29326236 | 0.82 | NPEPPS (0.44) | CYP2C9NPEPPSTDP1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | CYP11B1 3367/4885CYP11B2 1461/4885PRMT5 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.