Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178819 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1CASP3HPGDALDH1A1 | |
| SCHEMBL22572494 | 0.84 | PLAAT3 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL11390257 | 0.76 | TDP1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL21100446 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2FFAR1L3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL104964 | 0.76 | ESR1 (0.49) | SLC5A1SLC5A2TDP1HSD17B10HPGD | |
| SCHEMBL5800604 | 0.75 | TDP1 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL23758082 | 0.75 | GFER (0.43) | L3MBTL1ALDH1A1 | |
| SCHEMBL105767 | 0.74 | HSD17B10 (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL764952 | 0.74 | SMN1; SMN2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL661277 | 0.74 | PLAAT3 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | PLAAT3 128/4885PLAAT5 231/4885PLAAT2 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.