Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390257 | 0.90 | TDP1 (0.55) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL105765 | 0.88 | TDP1 (0.62) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL22599471 | 0.87 | IAPP (0.49) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL22414097 | 0.85 | ESR1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4IAPP | |
| SCHEMBL27049124 | 0.83 | MAOB (0.47) | IAPPHSD17B10RXRARXRBRXRG | |
| SCHEMBL8809801 | 0.83 | HPGD (0.50) | TDP1IAPPFFAR1HSD17B10SLC5A1 | |
| SCHEMBL3642535 | 0.82 | HDAC1 (0.64) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL30911279 | 0.81 | PLAAT3 (0.47) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL23842282 | 0.81 | ALDH1A1 (0.56) | HSD17B10ALDH1A1HPGDSLC6A3 | |
| Ammonia Solution, Strong SCHEMBL6014478 | 0.81 | HDAC1 (0.62) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | UNIVERSITY PUBLIC CORPORATION OSAKA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | UNIVERSITY PUBLIC CORPORATION OSAKA (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-1691811-A1 | COMBINATION OF A SEDATIVE AND A NEUROTRANSMITTER MODULATOR, AND METHODS FOR IMPROVING SLEEP QUALITY AND TREATING DEPRESSION | Sepracor, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005060968-A1 | COMBINATION OF A SEDATIVE AND A NEUROTRANSMITTER MODULATOR, AND METHODS FOR IMPROVING SLEEP QUALITY AND TREATING DEPRESSION | SEPRACOR INC. (US) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | YWHAZ, YWHAH, PTPN21 | TDP1 1911/4885L3MBTL1 2977/4885PLAAT3 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.