Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326266 | 0.85 | NR1H2 (0.47) | NR1H2NR1H3NAMPTRXRAEED | |
| SCHEMBL31056864 | 0.82 | NR1H2 (0.45) | NR1H2NR1H3NAMPTNPC1RAB9A | |
| SCHEMBL29328205 | 0.80 | NR1H2 (0.44) | NR1H2NR1H3NAMPTUCHL1USP30 | |
| SCHEMBL29326263 | 0.78 | NR1H2 (0.47) | NR1H2NR1H3RAB9AALDH1A1 | |
| SCHEMBL28961486 | 0.74 | NR1H2 (0.48) | NR1H2NR1H3UCHL1USP30NPC1 | |
| SCHEMBL5529036 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL4967238 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL4967606 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL29321110 | 0.72 | NR1H2 (0.45) | NR1H2NR1H3NAMPTRXRAMEN1 | |
| SCHEMBL27284777 | 0.72 | NR1H2 (0.46) | NR1H2NR1H3UCHL1USP30NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |