Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326266 | 0.86 | NR1H2 (0.47) | NR1H2NR1H3ALDH1A1KDM4EGAA | |
| SCHEMBL29326644 | 0.82 | NR1H2 (0.44) | NR1H2NR1H3ALDH1A1KDM4EGAA | |
| SCHEMBL29328205 | 0.80 | NR1H2 (0.44) | NR1H2NR1H3ALDH1A1KDM4EGAA | |
| SCHEMBL29326263 | 0.78 | NR1H2 (0.47) | NR1H2NR1H3ALDH1A1RAB9A | |
| SCHEMBL28961486 | 0.75 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1GAALMNA | |
| SCHEMBL4967238 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3ALDH1A1LMNANPSR1 | |
| SCHEMBL5529036 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3ALDH1A1LMNANPSR1 | |
| SCHEMBL4967606 | 0.74 | RIPK1 (0.48) | NR1H2NR1H3ALDH1A1LMNANPSR1 | |
| SCHEMBL27949195 | 0.73 | LMNA (0.46) | ALDH1A1GAALMNANPSR1MEN1 | |
| SCHEMBL27284777 | 0.73 | NR1H2 (0.46) | NR1H2NR1H3ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |