Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 5/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HCN1 | O60741 | 1/20 | 0.39 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326266 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL31056864 | 0.78 | NR1H2 (0.45) | NR1H2NR1H3ALDH1A1RAB9A | |
| SCHEMBL29326644 | 0.78 | NR1H2 (0.44) | NR1H2NR1H3ALDH1A1RAB9A | |
| SCHEMBL29328205 | 0.76 | NR1H2 (0.44) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL16055979 | 0.73 | CSF1R (0.49) | LRRK2ALDH1A1RAB9A | |
| SCHEMBL3156851 | 0.73 | YAP1 (0.54) | TLR9YAP1 | |
| SCHEMBL31056740 | 0.72 | NR1H2 (0.49) | NR1H2NR1H3YAP1TMEM97SIGMAR1 | |
| SCHEMBL31056635 | 0.72 | NR1H2 (0.48) | NR1H2NR1H3YAP1TMEM97SIGMAR1 | |
| SCHEMBL30930678 | 0.71 | TMEM97 (0.58) | TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL28961486 | 0.71 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |