Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.47 |
| ▸ | HPGDS | O60760 | 3/20 | 0.46 |
| ▸ | IL1B | P01584 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 6/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326604 | 0.89 | SCN9A (0.47) | SCN9AHPGDSIL1BFPR2PDE2A | |
| SCHEMBL29326794 | 0.86 | NLRP3 (0.41) | SCN9AIL1BFPR2 | |
| SCHEMBL29326790 | 0.82 | HPGDS (0.38) | SCN9AHPGDSIL1BFPR2 | |
| SCHEMBL29326755 | 0.79 | KCNH2 (0.46) | IL1B | |
| SCHEMBL29326772 | 0.79 | IL1B (0.65) | IL1B | |
| SCHEMBL29326785 | 0.76 | IL1B (0.48) | IL1BPDE2A | |
| SCHEMBL29326740 | 0.76 | IL1B (0.40) | IL1BPDE2A | |
| SCHEMBL29326501 | 0.74 | NLRP3 (0.49) | SCN9AIL1BFPR2 | |
| SCHEMBL29326505 | 0.74 | NLRP3 (0.49) | SCN9AIL1BFPR2 | |
| SCHEMBL29326601 | 0.72 | NLRP3 (0.35) | SCN9AHPGDSIL1BFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | SCN9A 3093/4885HPGDS 3900/4885IL1B 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.