Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18043582 | 0.86 | GPR119 (0.60) | TP53GPR119LMNA | |
| SCHEMBL23777806 | 0.86 | STS (0.48) | TP53GPR119 | |
| SCHEMBL30594074 | 0.86 | GPR119 (0.60) | TP53GPR119LMNA | |
| SCHEMBL18061525 | 0.86 | GPR119 (0.60) | TP53GPR119LMNA | |
| SCHEMBL13835355 | 0.85 | MEN1 (0.46) | TP53GPR119 | |
| SCHEMBL19690138 | 0.85 | USP30 (0.50) | USP30GPR119RORC | |
| SCHEMBL19690137 | 0.85 | USP30 (0.50) | USP30GPR119RORC | |
| SCHEMBL23784981 | 0.84 | ADAMTS5 (0.52) | GRM5GRM1TP53GPR119LMNA | |
| SCHEMBL23784980 | 0.84 | ADAMTS5 (0.52) | GRM5GRM1TP53GPR119LMNA | |
| SCHEMBL29327279 | 0.84 | HDAC1 (0.47) | GRM5GRM1TP53USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | AQP3, SLC6A7, ABCG2 | GRM5 589/4885GRM1 2308/4885TP53 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.