Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329871 | 0.81 | RET (0.39) | PRKCQSYK | |
| SCHEMBL29330024 | 0.81 | MAOB (0.37) | PRKCQABL1BCRSYK | |
| SCHEMBL29328592 | 0.78 | SYK (0.45) | PRKCQSYK | |
| SCHEMBL29330430 | 0.78 | PRKCQ (0.43) | PRKCQABL1SYK | |
| SCHEMBL24539134 | 0.78 | JAK2 (0.44) | PRKCQPIK3CASYKPDGFRB | |
| SCHEMBL30629373 | 0.78 | JAK2 (0.44) | PRKCQPIK3CASYKPDGFRB | |
| SCHEMBL29328808 | 0.78 | PRKCQ (0.41) | PRKCQSYK | |
| SCHEMBL29329434 | 0.77 | MAPT (0.43) | PRKCQSYK | |
| SCHEMBL29329292 | 0.76 | SIRT2 (0.41) | PRKCQSYK | |
| SCHEMBL29330342 | 0.75 | SYK (0.40) | PRKCQABL1BCRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |