Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330430 | 0.89 | PRKCQ (0.43) | SIRT2SIRT1SIRT3PRKCQMAPT | |
| SCHEMBL29329869 | 0.86 | ESR1 (0.42) | SIRT2SIRT1SIRT3MAPTTP53 | |
| SCHEMBL29329944 | 0.86 | SIRT2 (0.41) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29330342 | 0.85 | SYK (0.40) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29330433 | 0.84 | SYK (0.41) | SIRT2SIRT1SIRT3PRKCQMAOB | |
| SCHEMBL29329290 | 0.83 | PRKCQ (0.42) | PRKCQSYKMETPRKCD | |
| SCHEMBL29330166 | 0.82 | PRKCQ (0.39) | PRKCQMAPTNPC1TP53GAA | |
| SCHEMBL29329871 | 0.82 | RET (0.39) | SIRT2SIRT1SIRT3PRKCQMAPT | |
| SCHEMBL29330563 | 0.81 | PRKCQ (0.39) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29330425 | 0.80 | ESR1 (0.42) | PRKCQMAPK1SYKMETPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |