Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328592 | 0.86 | SYK (0.45) | RETSYKPRKCQMAPTAPP | |
| SCHEMBL29330024 | 0.85 | MAOB (0.37) | SYKPRKCQESR1PRKCDSIRT2 | |
| SCHEMBL29330430 | 0.82 | PRKCQ (0.43) | SYKPRKCQMAPTAPPMEN1 | |
| SCHEMBL29329292 | 0.82 | SIRT2 (0.41) | SYKPRKCQMAPTAPPMAPK1 | |
| SCHEMBL29328886 | 0.81 | PRKCQ (0.45) | SYKPRKCQ | |
| SCHEMBL29330342 | 0.79 | SYK (0.40) | RETSYKPRKCQAPPESR1 | |
| SCHEMBL29329434 | 0.79 | MAPT (0.43) | SYKPRKCQMAPTMEN1POLB | |
| SCHEMBL29329215 | 0.79 | SYK (0.40) | RETSYKPRKCQMAPTAPP | |
| SCHEMBL29329290 | 0.78 | PRKCQ (0.42) | RETSYKPRKCQESR1PRKCD | |
| SCHEMBL29329004 | 0.76 | PRKCQ (0.38) | RETSYKPRKCQESR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |