Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329871 | 0.86 | RET (0.39) | SYKPRKCQMAPK1MEN1POLB | |
| SCHEMBL29330430 | 0.80 | PRKCQ (0.43) | SYKPRKCQMEN1KMT2AMAPT | |
| SCHEMBL29330024 | 0.80 | MAOB (0.37) | SYKPRKCQESR1PRKCD | |
| SCHEMBL29330342 | 0.79 | SYK (0.40) | SYKPRKCQRETESR1APP | |
| SCHEMBL29329215 | 0.79 | SYK (0.40) | SYKPRKCQMAPK1MEN1POLB | |
| SCHEMBL29329292 | 0.78 | SIRT2 (0.41) | SYKPRKCQMAPK1MAPTAPP | |
| SCHEMBL29329435 | 0.78 | PRKCQ (0.36) | SYKPRKCQRETESR1PRKCD | |
| SCHEMBL29328745 | 0.78 | PRKCQ (0.37) | SYKPRKCQRETESR1APP | |
| SCHEMBL29330433 | 0.77 | SYK (0.41) | SYKPRKCQRETESR1PRKCD | |
| SCHEMBL29329004 | 0.76 | PRKCQ (0.38) | SYKPRKCQRETESR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |