Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329290 | 0.91 | PRKCQ (0.42) | PRKCQEGFRSYK | |
| SCHEMBL29329292 | 0.89 | SIRT2 (0.41) | PRKCQMAPTAPPSIRT2SIRT1 | |
| SCHEMBL29330342 | 0.89 | SYK (0.40) | PRKCQEGFRAPPSIRT2SIRT1 | |
| SCHEMBL29330345 | 0.88 | PRKCQ (0.38) | PRKCQEGFRTTBK1TTBK2AURKB | |
| SCHEMBL29330428 | 0.88 | ESR1 (0.42) | PRKCQEGFRMAOBSYKABL1 | |
| SCHEMBL29329369 | 0.88 | PRKCQ (0.34) | PRKCQEGFRAPPSIRT2SIRT1 | |
| SCHEMBL29329528 | 0.88 | SYK (0.36) | PRKCQMAPTSIRT2SIRT1SIRT3 | |
| SCHEMBL29329869 | 0.87 | ESR1 (0.42) | MAPTSIRT2SIRT1SIRT3MAOB | |
| SCHEMBL29330433 | 0.86 | SYK (0.41) | PRKCQSIRT2SIRT1SIRT3MAOB | |
| SCHEMBL29330567 | 0.85 | PRKCQ (0.45) | PRKCQTTBK1TTBK2SYKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |