Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329056 | 0.85 | ECE1 (0.39) | ALDH1A1ECE1MEN1KMT2ACASP2 | |
| SCHEMBL19199459 | 0.84 | MEN1 (0.54) | ALDH1A1MEN1KMT2ACASP2NAAA | |
| SCHEMBL24398829 | 0.84 | ALDH1A1 (0.38) | ALDH1A1ECE1MEN1KMT2ALMNA | |
| SCHEMBL29329050 | 0.84 | MEN1 (0.40) | ALDH1A1ECE1MEN1KMT2ATSHR | |
| SCHEMBL18866882 | 0.83 | CASP2 (0.53) | ALDH1A1CASP2SMN1; SMN2NAAAFAAH | |
| SCHEMBL16248535 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CASP2TSHRLMNAPKM | |
| SCHEMBL20223530 | 0.81 | KMT2A (0.46) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL18134694 | 0.80 | LMNA (0.44) | ALDH1A1KMT2ASMN1; SMN2LMNAPKM | |
| SCHEMBL25443782 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ECE1MEN1KMT2ALMNA | |
| SCHEMBL25173385 | 0.79 | CYP2D6 (0.46) | ALDH1A1ECE1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |