Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329063 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AFAAHALDH1A1ECE1 | |
| SCHEMBL29329056 | 0.82 | ECE1 (0.39) | MEN1KMT2AALDH1A1ECE1 | |
| SCHEMBL19199459 | 0.78 | MEN1 (0.54) | MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL22280196 | 0.77 | MEN1 (0.52) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL24398829 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1ECE1 | |
| SCHEMBL25443782 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1ECE1 | |
| SCHEMBL8909886 | 0.77 | MEN1 (0.45) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL13373640 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHMAPK1EPHX1 | |
| SCHEMBL13373705 | 0.76 | RAB9A (0.43) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL18866882 | 0.76 | CASP2 (0.53) | FAAHALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |