Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 5/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329163 | 0.75 | MAPT (0.40) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29328879 | 0.74 | CYP3A4 (0.37) | SMN1; SMN2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29328840 | 0.63 | ALDH1A1 (0.38) | SMN1; SMN2MAOBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4528011 | 0.61 | AGBL2 (0.51) | LMNA | |
| SCHEMBL30349490 | 0.61 | AGBL2 (0.51) | LMNA | |
| SCHEMBL9952921 | 0.60 | PLAU (0.36) | LMNA | |
| SCHEMBL18517808 | 0.60 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL14952144 | 0.60 | RAB9A (0.35) | SMN1; SMN2NPC1RAB9AKCNJ6KCNJ5 | |
| SCHEMBL14952430 | 0.59 | TSHR (0.36) | SMN1; SMN2NPC1RAB9AKCNJ6KCNJ5 | |
| SCHEMBL15996190 | 0.58 | BACE1 (0.56) | SMN1; SMN2NPC1RAB9AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149676-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-18 | — | — | WO | disclosed |